School of Pharmaceutical
Sciences of Ribeirão Preto

University of São Paulo

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Presentation

Department of Physics and Chemistry

          The Physics and Chemistry Department has 28 professors responsible for 3625 class hours/year in FCFRP (School of Pharmaceutical Sciences of Ribeirão Preto) and 210 class hours/year in FORP (School of Dentistry of Ribeirão Preto).

            Regarding the teaching activities, the Department aims to provide solid basic knowledge, develop critical scientific sense and specific intellectual abilities, mandatory capabilities for the pharmacist training; regarding the scientific area, the Department aims to generate, expand, consolidate and disseminate knowledge, scientific and technological methodologies coupled with the formation of high-level professionals; through extension activities, it aims to intensify the sharing of departmental activities with society, both through diffusion of knowledge and providing access to high complexity instrumentation. These goals are articulated with the Unit goals in order to jointly conduct integrated and continuous efforts related to the qualification of the pharmacist and to the basic and applied research in order to contribute to the development of the pharmaceutical and related areas, especially in areas that are potentially important for the Society.

            The Department aims to participate actively in the training process in Pharmaceutical Sciences with solid general education and deep basic training. Developing skills to work in the pharmaceutical market with high ethical and humanistic training and ability to perform their profession are aimed.

            Because of its diversity, with researchers linked to the areas of chemistry, physics, mathematics and biology, the Department has worked to strengthen thematic groups based the theme DRUGS. An example, it can be seen projects based on the synthesis, characterization, analysis and evaluation of biological activity of nitrosyl ruthenium compounds and counts with the participation of DPQ professors from different areas of expertise (inorganic chemistry, analytical chemistry and pharmacology) and others from the unit and beyond. The second thematic issue that also joins the professors of the Department is the research in natural products, vegetables and marine organisms in the search for compounds with pharmacological activity. About 50% of the Department's researchers develop research related to the isolation, structure elucidation, analysis and evaluation of pharmacological properties of products from natural sources (plants, algae, animals). The biological physics group has been developing projects aimed at determining the structures of proteins by X-ray diffraction, use of numerical simulation and techniques of statistical mechanics popularly known as "molecular modeling" and physicochemical characterization of target molecules for planning drugs as a tool to fight against recurrent diseases, as leishmaniasis and Chagas disease. This group also develops studies in order to perform physicochemical characterization to understand the complexation of protein-protein and protein-polysaccharide in order to understand the transportation of drugs across membranes (microencapsulation).